Decision Circuits Journal Club

We're discussing recent papers in systems neuroscience with a focus on quantitative behavior, cortical dynamics, cell-types, and neuromodulation.

We meet bi-weekly on Wednesday at 4pm on Campus Nord (between Luisenstraße and Philippstraße) on days without BCCN seminar talks.

If you'd like to join the discussion please let Antonio know and we'll add you to our e-mail reminders with details on upcoming dates (about one e-mail per meeting/week).

DateTimePresenterTitleDOIPrimer
20.09.20234pmAntonioGrove…Knight (2023). Dopamine subsystems that track internal states. Naturehttps://doi.org/10.1038/s41586-022-04954-0Distinct dopamine neurons in the VTA respond to ‘internal states’ tracking hydration and nutrition
14.09.20239.30amDariyaYun…Parker (2023). Antipsychotic drug efficacy correlates with the modulation of D1 rather than D2 receptor-expressing striatal projection neuronshttps://doi.org/10.1038/s41593-023-01390-9This paper uses the novel hallucination-like perception task (cf Schmack et al, Science) to study striatal circuits for psychosis and antipsychotics.
07.09.20239.30amGregSohn … Jazayeri (2019). Bayesian Computation through Cortical Latent Dynamics. Neuronhttps://doi.org/10.1016/j.neuron.2019.06.012Population states in primate PFC encode both the prior and temporal estimate to guide behavior
15.06.20239.30amVictoriaShen..Glimcher (2023). Flexible control of representational dynamics in a disinhibition-based model of decision making. eLifehttps://doi.org/10.7554/eLife.82426Spiking neural network model that includes both inhibitory and disinhibitory cell types reproduces decision-making features
25.05.20239.30amEricVargas..Olson (2023). Psychedelics promote neuroplasticity through the activation of intracellular 5-HT2A receptors. Sciencehttps://doi.org/10.1126/science.adf0435Psychedelics unfolder their neuroplastic effects not via regular membrane-bound 5HT2A receptors, but by going into the cell
20.04.20239.30amEricTorrado Pacheco … Moghaddam (2023). Acute psilocybin enhances cognitive flexibility in rats. Neurophsychopharmacologyhttps://doi.org/10.1038/s41386-023-01545-zPsilocybin changes reversal learning in a 2A dependent way
13.04.20239.30amLillyHyun..Kwon (2023). Serotonin in the orbitofrontal cortex enhances cognitive flexibility. BioRxivhttps://doi.org/10.1101/2023.03.09.531880Serotonin specifically in OFC changes speed of reversal learning
23.03.20239.30amVictoriaAklan…Atasoy (2023). Dorsal raphe serotonergic neurons suppress feeding through redundant forebrain circuits. Molecular Metabolismhttps://doi.org/10.1016/j.molmet.2023.101676Specific dorsal raphe 5HT neurons suppress feeding (to LH and BNST)
16.02.20239.30amVictoriaDiehl,Redish (2023). Differential processing of decision information in subregions of rodent medial prefrontal cortex. eLifehttps://doi.org/10.7554/eLife.82833mPFC subregion coding of decision variables during economic decisions
09.02.20239.30amGregPandarinath…Susillo (2018). Inferring single-trial neural population dynamics using sequential auto-encoders. Nature Methodshttps://doi.org/10.1038/s41592-018-0109-9Novel method to model single-trial spike trains using RNN-based autoencoders.
02.02.20239.30amEricPomrenze … Malenka (2022). Modulation of 5-HT release by dynorphin mediates social deficits during opioid withdrawal. Neuronhttps://doi.org/10.1016/j.neuron.2022.09.0245HT in the striatum is important for social deficits related to addiction
26.01.20239.30amLillyPaquelet … Miller (2022). Single-cell activity and network properties of dorsal raphe nucleus serotonin neurons during emotionally salient behaviors. Neuronhttps://doi.org/10.1016/j.neuron.2022.05.015Different subpopulation of dorsal raphe 5HT neurons (grouped by projection) are differentially sensitive to reward/social/shock/anxiety cues
12.01.20239.30amVictoriaJeong … Namboodiri (2022). Mesolimbic dopamine release conveys causal associations. Sciencehttps://doi.org/10.1126/science.abq6740A novel, causal framework and model for association learning (as opposed to RL)
9.30amAntonioKlein-Fluegge, … Rushworth (2022). Medial and orbital frontal cortex in decision-making and flexible behavior. Neuronhttps://doi.org/10.1016/j.neuron.2022.05.022Value and choice coding along OFC regions
20.10.20229.30amGregSylwestrak…Sussillo, Deisseroth (2022) Cell-type-specific population dynamics of diverse reward computations. Cellhttps://doi.org/10.1016/j.cell.2022.08.019Functional groups of neurons in the habenula encode reward prediction, outcome, and history and are modelled with cell-type LFADS

This notion page is synced with https://torbenottlab.org/decision-circuits-journal-club.